Christopher Nolan's Inception has topped the North American box office taking $60.4m (£39.5m) on its opening weekend, according to studio estimates.
The thriller, about thieves who steal secrets from dreams, knocked animated 3D film Despicable Me off the top spot.
It was Leonardo DiCaprio's best opening weekend, beating $41.1m (£26.9m) taken for Shutter Island in February. It is already being tipped for Oscar glory.
Disney's The Sorcerer's Apprentice opened at three with $17.4m (£11.4m).
Inception stars DiCaprio, 35, as the leader of a team that breaks into people's dreams.
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